Showing posts with label Cell Construction Project BIO 156. Show all posts
Showing posts with label Cell Construction Project BIO 156. Show all posts

Friday, February 15, 2008

Cell Model

Animal Cell Model

This is the model of an animal cell utilizing various beads, gems, ribbons, thread and other craft items. I constructed the cell, along with an example of DNA, RNA, the process of mitosis, and the process of transcription and translation. The project began as this:


The beginning...

and continues...

My cell consists of the following:
  • Cell - large white styrofoam disc
  • Cell membrane- dark purple ribbon
  • Ribosomes- small pink gems
  • Lysosomes- dark purple gems
  • Vesicles- light purple gems
  • Endoplasmic Reticulum- folded purple ribbon
  • Golgi Apparatus- folded light purple ribbon
  • Mitochondria- striated pink glass beads
  • Centrosome- red star
  • Microtubules (cilia, flagella)- toothpicks
  • Nucleus- small white styrofoam disc
  • Nuclear membrane-compiled dark purple ribbon with light purple dotted overlay (for nuclear pores)
  • Nucleolus- black button
  • Chromatin- purple thread
  • Chromosomes- purple and blue pipe cleaners






Prior to completing the cell model, I constructed the following pictures to represent the following, as I could not fit them into my completed cell model:



DNA Ladder Structure

Although normally a double helix, the above picture represents DNA in ladder structure:
  • White buttons- phosphates
  • Pink gems- deoxyribose sugar
  • Blue gems- thymine
  • Yellow gems- adenine
  • Red Gems- cytosine
  • Green gems- guanine
Notice that the strands are antiparallel.



Structure of RNA

The above picture represents RNA:
  • White buttons- phosphate
  • Pink gems- ribose
  • Green gems- guanine
  • Purple gems- uracil (instead of thymine in DNA)
  • Yellow gems- adenine
  • Red gems- cytosine

The following pictures represent transcription and translation:


Transcription

Transcription occurs within the nucleus. The DNA molecule serves as a template for RNA. The mRNA is processed prior to leaving the nucleus. The mRNA leaves the nucleus a mature mRNA through the disintegrating nuclear membrane.
  • Green pipe cleaner -DNA
  • Purple pipe cleaner- mRNA
  • Green gems- guanine
  • Red gems- cytosine
  • Yellow gems- adenine
  • Purple gems- uracil
  • Blue gems- thymine
  • White area- nucleus


Translation occurs outside the nucleus:


mRNA moving into cytoplasm to ribosomes

  • White button- nuclear pore
  • Purple pipe cleaner- mRNA
  • Coconut doughnut- small and large ribosomal subunits


tRNA

  • Oblong green gems- tRNA
  • Red-Yellow-Purple gem chain- anticodon
  • Blue gem/yellow gem- peptides

tRNAs with anticodons carry amino acids to mRNA. Inside the ribosomal subunits, the anticodon-codon base pairing occurs and the polypeptide synthesis takes place one amino acid at a time.


Translation

  • White area- cytoplasm
  • Coconut doughnut- ribosome
  • Large purple beads strung together- peptides
  • Purple pipe cleaner- mRNA
  • Oblong green gems- tRNA
  • Bottom row of gems along purple pipe cleaner grouped in 3's- codons
  • Group of gems by 3's near the green oblong gem- anticodons
Mitosis is duplication division. The following pictures represent mitosis:
  • Purple and blue pipe cleaners-chromosomes/sister chromatids
  • Purple thread- Chromatin
  • Brown thread- spindle fibers
  • Pink gems- spindle poles


Early prophase-centrosomes have duplicated, chromatin is condensing


Prophase- nucleolus has disappeared and duplicated chromosomes are visible, spindle in the process of forming


Early metaphase- each chromatid is attached to a spindle fiber, spindle fibers stretch from each pole and overlap


Metaphase-centromeres of duplicated chromosomes are aligned at the equator, spindle fibers are attached to the sister chromatids come from opposite spindle poles


Anaphase-sister chromatids part and become daughter chromosomes that move toward spindle poles (obviously the cells would still be pulling apart and not separate yet)


Telophase-daughter cells are forming as nuclear envelopes and nucleoli reappear


The final product...


Animal cell completion with key




Completed cell

  • Cell - large white styrofoam disc
  • Cell membrane- dark purple ribbon
  • Ribosomes- small pink gems
  • Lysosomes- dark purple gems
  • Vesicles- light purple gems
  • Endoplasmic Reticulum- folded purple ribbon
  • Golgi Apparatus- folded light purple ribbon
  • Mitochondria- striated pink glass beads
  • Centrosome- red star
  • Microtubules (cilia, flagella)- toothpicks
  • Nucleus- small white styrofoam disc
  • Nuclear membrane-compiled dark purple ribbon with light purple dotted overlay (for nuclear pores)
  • Nucleolus- black button
  • Chromatin- purple thread
  • Chromosomes- purple and blue pipe cleaners


View of cell showing cell membrane and nuclear membrane